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[9] It is on the World Health Organization's List of Essential Medicines

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Since l-carnitine alters the expression of glutamate dehydrogenase, which is involved in urea cycle, it seems likely that changes in BUN levels are independent from the effects of l-carnitine on kidney function but is caused by altered urea production in the liver

Selective modulation of the PKC/p38MAP kinase signalling pathway for the antidepressant-like activity of amitriptyline