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Cell Biosci 11 , 217 (2021)

Recently several groups have developed platelet substitutes using engineered biomaterials, for examples, ultrasoft microgel-based platelet-like particles that interact with fibrin networks 19 and plasmin-responsive liposomal nanoparticles that expose phosphatidylserine to promote coagulation at injury sites 20

Erianin significantly inhibits the proliferation, invasion and migration of GC cells by dually regulating the PI3K/AKT and liver kinase b1/salt-inducible kinase 2 or 3/par-3 family cell polarity regulator (LKB1/SIK2/3/PARD3) signaling pathways (37)

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For a medicine to earn clear dosing guidance, researchers generally need repeated studies, defined outcomes, safety data, and a regulated product