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Retention time and detected m/z were used to annotate lipid species according to the Lipid Classification System guidelines of LIPID MAPS Structure Database (LMSD) [83] (max 0.005 Da error), while single lipid species identification was substantiated by MS2 fragmentation (see Supplementary Table 2)

For prevention of contrast-induced acute kidney injury, a meta-analysis found misleading beneficial associations that were lost when analysis was restricted to larger studies (52) , and mechanistic studies showed that oral NAC is poorly absorbed with no renoprotective effects (53)