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CS-induced oxidative stress is responsible for altered cellular metabolism, including increased infiltrating immune cells, pro-inflammatory cytokine production, proteaseantiprotease imbalance, lipid peroxidation, apoptosis, upregulation of unfolded protein response (UPR), and protein misfolding

But there were some inevitable reasons the Spice market went that way

Clinical trials and experimental animal studies reported the beneficial effects of colchicine against CVDs [22, 23, 25, 28, 29]

Instead, try to focus on what is happening now, not what you might have to deal with in the future

CV ailments accounted for more than half of the health risks (6, 73)